Immunological prognosing of complications of locomotors trauma

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The immunological effects of trauma

Trauma, both surgical as occurs during an elective operation, and accidental as in the burn or road traffic accident victim, is associated with a relative state of immunosuppression. Why this apparently deleterious response should happen remains unexplained, but our understanding of the interactions within the immune system during trauma is increasing dramatically. The use of monoclonal antibod...

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Immunological consequences of trauma and shock.

The immune system is a powerful, complex entity composed of numerous cell types and regulated by autocrine, paracrine, and hormonal mechanisms. Trauma and haemorrhagic shock induce numerous changes within this system which are ultimately deleterious and contribute to the high incidence of organ dysfunction and infectious complications seen following injury. Regional hypoxia and depletion of int...

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Coagulation complications following trauma

Traumatic injury is one of the leading causes of death, with uncontrolled hemorrhage from coagulation dysfunction as one of the main potentially preventable causes of the mortality. Hypothermia, acidosis, and resuscitative hemodilution have been considered as the significant contributors to coagulation manifestations following trauma, known as the lethal triad. Over the past decade, clinical ob...

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Thromboembolic complications following trauma.

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ژورنال

عنوان ژورنال: Frontiers in Immunology

سال: 2013

ISSN: 1664-3224

DOI: 10.3389/conf.fimmu.2013.02.00035